Welcome to Lab Test Consult

You can log in and post your comments

Share your knowledge and experience!

Member Login
Lost your password?

Research provides diabetes hope

January 16, 2012
By

Professor Andy SewellAndy Sewell says the process of the body attacking insulin-producing cells is not fully understood

Scientists say they have uncovered new evidence which it is hoped could eventually help diagnose and prevent type 1 diabetes.

Professor Andy Sewell of Cardiff University, working with King’s College London, witnessed human T-cells – which protect against disease – inadvertently destroying insulin-producing cells.

Insulin controls blood sugar levels and a lack of it can be fatal.

More than 160,000 people in Wales have been diagnosed with diabetes.

Prof Sewell, an expert in human T-cells from Cardiff University’s School of Medicine, worked alongside diabetes experts from King’s College.

Scientists isolated a T-cell from a patient with type 1 diabetes to view a process which results in the killing of insulin-producing cells in the pancreas.

It is the first time the process has been witnessed.

“This is a breakthrough and tells us where we can now focus in the future,” said Professor Sewell, speaking on BBC Radio Wales.

He said people can have type 1 diabetes long before being diagnosed so, potentially in the future, at risk groups could be identified and then treated earlier.

“Type 1 diabetes is a result of the body’s own immune system attacking and destroying the cells in the pancreas that manufacture the hormone insulin,” he said.

Continue reading the main story

Start Quote

This knowledge will be used in the future to help us predict who might get the disease and also to develop new approaches to prevent it”

End Quote
Professor Mark Peakman
King’s College, London

“Insulin controls blood sugar levels and a lack of insulin is fatal if untreated.

“The mechanism by which the body attacks its own insulin producing cells in the pancreas is not fully understood.

“Our findings show how killer T-cells might play an important role in autoimmune diseases like diabetes and we’ve secured the first ever glimpse of the mechanism by which killer T-cells can attack our own body cells to cause disease.”

Professor Mark Peakman from the National Institute for Health Research (NIHR) Biomedical Research Centre at King’s College, London, said: “This first sight of how killer T-cells make contact with the cells that make insulin is very enlightening, and increases our understanding of how type 1 diabetes may arise.

“This knowledge will be used in the future to help us predict who might get the disease and also to develop new approaches to prevent it.

“Our aim is to catch the disease early before too many insulin-producing cells have been damaged.”

Article source: http://www.bbc.co.uk/go/rss/int/news/-/news/uk-wales-16560844

Share

Related posts:

  1. ‘Gene test’ cancer research hope
  2. Diabetes: FDA provides guidance on artificial pancreas
  3. Why Coffee May Reduce Diabetes Risk
  4. Intensive Control of Type 1 Diabetes Helps Kidneys: Study
  5. Diabetes Type 1 As It Unfolds
  6. Diabetes Denial a Big-Time Problem
  7. Treating Diabetes with Insulin: Real-Life Tips
  8. New study identifies the cause of diabetes misdiagnosis among Asian Americans
  9. Holiday Travel Tips for People With Diabetes
  10. Tools for predicting diabetes exist but are not used, research shows

Tags:



New post

Posts

December 2018
M T W T F S S
« Aug    
 12
3456789
10111213141516
17181920212223
24252627282930
31  

Posts

Recent comments

    Contact Sign In

    Email Marketing You Can Trust